The effects of magnesium supplementation on blood pressure and obesity measure among type 2 diabetes patient: a systematic review and meta-analysis of randomized controlled trials. Asbaghi O, Hosseini R, Boozari B, et al.The effects of resveratrol on glycemic control and cardiometabolic parameters in patients with T2DM: a systematic review and meta-analysis. Abdelhaleem IA, Brakat AM, Adayel HM, et al.A 2019 meta-analysis and review of 83 studies concluded that omega-3 supplementation had little to no effect on plasma glucose, fasting insulin, HBA1C, and insulin resistance markers. A 2022 meta-analysis and review of 26 papers on omega-3 supplementation had the same conclusion, stating that omega-3 supplementation did not improve glycemic outcomes in patients with diabetes.A 2020 meta-analysis of 12 studies found that fish oil supplementation for people with type 2 diabetes did not impact their glycemic control.A 2022 review and meta-analysis of 30 studies regarding omega-3s and diabetes found that omega-3 supplementation led to a significant reduction in fasting blood glucose and insulin resistance markers.A 2008 Cochrane systematic review of 23 randomized controlled trials involving 1,075 participants found that omega-3 supplementation in people with type 2 diabetes has no statistically significant effect on glycemic control or fasting insulin.A 2017 American Heart Association science advisory based on 5 studies with more than 10,000 participants concluded that overall evidence from randomized controlled trials suggests no benefit of omega-3 fatty acid supplements among patients with or at risk for diabetes to prevent cardiovascular disease.
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